The Acinar Redeemer

Acinar cell neoplasms arise from the acinar cells of the pancreas. Normal acinar cells are the primary cells of the exocrine pancreas and are responsible for secreting various enzymes. These tumors are distinct from the more common adenocarcinomas of the pancreatic ducts. Because the tumors arise from normal acinar cells, the tumor cells also may secrete pancreatic enzymes, most commonly lipase. This is a rare cancer. Jenny was one of the patients who suffered from abdominal or back pain, and no lipase hypersecretion syndrome. She had to be resected cases to increase her survivability. However, it could only extend up to 5 years at most. Jenny presenting with low grade fever and mid-abdominal tenderness secondary to a pancreatic mass with acinar and endocrine differentiation metastatic to the liver. She received multiple lines of conventional and investigational chemotherapy regimens. This included cycles of gemcitabine, irinotecan, oxaliplatin, docetaxel, capecitabine, octreotide, leucovorin, 5- fluorouracil, cisplatin, protein kinase C inhibitor, tyrosine kinase inhibitor, and a novel taxane. The patient developed Clostridium difficile colitis and septic shock resulting in death 49 months after the diagnosis of acinar cell carcinoma of the pancreas. Conclusion This is a case of acinar cell carcinoma of the pancreas with an endocrine component, treated with multiple chemotherapeutic agents, in which the patient survived 37 months after diagnosis. She sacrifices herself to the good of the society by contributing to the research whereby they eventually come up with ways to kills the cancer cell slowly.